The museum has four remarkable works by local artist Piero della Francesca (1415/1420-1492). Inparticular, note the very attractive polyptych of the Virgin of Mercy, and a Resurrection, a work by the artist at the height of his powers. There are also works by other local artists (Raffaellino del Colle), by Bassano, Signorelli and the School of Della Robbia.